1155 High level of population structuring within the West-African malaria vector Anopheles melas

Tuesday, December 14, 2010: 1:47 PM
Royal Palm, Salon 5-6 (Town and Country Hotel and Convention Center)
Michel A Slotman , Department of Entomology, Texas A&M University, College Station, TX
Kevin C Deitz , Entomology, Texas A&M University, College Station, TX
Michael R Reddy , Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT
Hans J Overgaard , Department of Mathematical Sciences and Technology, The Norwegian University of Life Sciences, Ås, Akershus, Norway
Abraham M Arnez , Medical Care Development International, Silver Spring, MD
Neha Satyanarayana , Department of Entomology, Texas A&M University, College Station, TX
Musa Jawara , Medical Research Council Laboratories, Fajara, Banjul, Gambia
Allesandra della Torre , Istituto Pasteur-Fondazione Cenci Bolognetti, Università di Roma "La Sapienza", Rome, Italy
Joao Pinto , Centro de Malária e outras Doenças Tropicais – Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, Lisbon, Portugal
Simon Abaga , Ministry of Health and Social Welfare, Malabo, Equatorial Guinea
Adalgisa Caccone , Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT
Anopheles melas is a brackish-water breeding mosquito that is a member of the An. gambiae complex, with a distribution that is limited to coastal marshlands from Senegal to Angola. Because of its limited distribution it is not considered a primary vector, although it is frequently an important vector locally, as is the case in several locations on Bioko Island, Equatorial Guinea. These Anopheles melas populations are subject to intensive vector control efforts under the Bioko Island Malaria Control Program II in support of the National Malaria Control Program of Equatorial Guinea. Understanding the population structure and migration patterns of this species is therefore important, because it can inform vector control efforts. We are analyzing An. melas populations throughout its range using microsatellites markers and a portion of the mitochondrial ND 4 and 5 genes to provide insight into the population structure of this species. We are particularly interested in estimating migration between the mainland and Bioko Island, as well as the effect of An. melas' patchy distribution on its population structure. Our results thus far suggest that An. melas is a highly structured species. Although Anopheles melas on Bioko Island belong to a single larger population, they appear to be isolated from mainland populations. Additionally, An. melas populations from The Gambia and Central Africa are highly differentiated and show little evidence of gene flow based on mtDNA. We are incorporating additional samples and populations in our data set, which will provide a detailed picture of the population structure of this malaria vector.

doi: 10.1603/ICE.2016.50973