Integrated anti-fungal defenses in subterranean termites: From cells to society

Subterranean termites have evolved disease resistance mechanisms that allow them to prevent the occurrence of fungal epizootics inside their nest. Such mechanisms include cellular immunity, production of antifungal compounds and hygienic behaviors. We suggest that these independent mechanisms interact in a synergistic manner to produce an efficient defense against fungal entomopathogens, by preventing the fungi from completing its life cycle in the termite's environment.