The potato tuberworm (PTW) Phthorimaea operculella (Zeller) is one of the most important potato pests worldwide. Typically found in tropical and subtropical regions, PTW was recently detected in Oregon in 2002. By 2005, PTW spread extensively across the Columbia Basin, the major potato production region of Oregon and Washington and currently threatens about 160,000 acres of potatoes valued at more than $500 million. Because it is a relatively new pest in this region, information on the distribution and biology of PTW in the Pacific Northwest is incomplete, hindering the development and implementation of effective control measures. Integrating management practices to control this pest in critical. Our comprehensive project will conduct research that will help potato growers effectively control this new pest in the region. Data from a region-wide pheromone trapping network started in 2004 indicate that PTW increased its geographical range in 2005. However, moth counts in 2006 were lower than the previous year in most areas. In chemical and cultural control trials, several pesticides proved effective at reducing PTW foliar and tuber damage, while cultural practices, such as irrigation after vine kill, covering potato hills with soil, and the use of certain desiccants, appear to reduce PTW tuber damage.