The soybean aphid, Aphis glycines Matsumura, a native of Asia, was first detected in the U.S. in 2000. Its current distribution extends throughout the North-Central U.S. and into Canada. Within this introduced range landscape structure has critical influences on the soybean aphid, its predators, and their interactions in agroecosystems. The impact of the predator community on soybean aphid population dynamics varied across 12 sites sampled in Michigan, Wisconsin, Minnesota and Iowa. In 4 of the 12 sites, predators had no impact on aphid population growth. In the remaining 8 sites, predators either delayed (4 sites) or prevented (4 sites) aphid populations from reaching threshold. We examined the relationship between coccinellid species abundance and the amount of non-crop habitat (woodlots, wetlands, pasturelands, grasslands, and urban areas) in the landscape as well as overall landscape heterogeneity. Exotic lady beetles (Harmonia axyridis, Hippodamia variegata, and Coccinella septempunctata) were positively correlated with non-crop habitat and habitat heterogeneity. Native lady beetle populations (Hippodamia convergens, Coleomegilla maculata, Cycloneda munda, and Hippodamia parenthesis) were negatively correlated with habitat heterogeneity; they were most abundant in homogeneous landscapes dominated by corn and soybean. These findings suggest that native and non-native predators of soybean aphid may be experiencing landscape influences in different ways.