DuPont Cyazypyr™ (DPX-HGW86, cyantraniliprole): a novel insecticide for aphid pest management and plant protection

DuPont Cyazypyr™ (DPX-HGW86, cyantraniliprole), is the third molecule of the diamide chemical class (IRAC Group 28 insecticides) to be commercialized, but the first that has cross-spectrum efficacy on sucking pests including key species of aphids, while conserving beneficial arthropods. Cyazypyr™ also controls other important agricultural pests including Lepidoptera, fruit flies, leafminers, leaf-feeding beetles, whiteflies, hoppers, psyllids, thrips and weevils. Aphids are major pests of important agronomic crops throughout the world, both through direct feeding damage to crops and the vectoring of important crop diseases. Like the other diamide compounds, Cyazypyr™ is a ryanodine receptor agonist, causing impairment of insect muscle function which results in rapid cessation of feeding. Cyazypyr™ has shown excellent efficacy on important aphid species, comparable to and even sometimes better than commercial standards. Cyazypyr™ has also consistently shown significant reduction of important aphid-vectored plant viruses. The product exhibits these characteristics and benefits with little to no impact on important aphid predators and parasitoids that complement the pest control. Cyazypyr™ controls insect populations that are resistant to other insecticides, thus there is no known cross resistance between Cyazypyr™ and other existing products. Therefore, Cyazypyr™ will be a valuable rotational partner in IPM and IRM programs.