D0023 Role of bursicon in larvae stage

Monday, December 13, 2010
Grand Exhibit Hall (Town and Country Hotel and Convention Center)
Qian Wang , Division of Plant Sciences-Entomology, University of MIssouri-Columbia, Columbia, MO
Qisheng Song , Division of Plant Sciences, University of Missouri, Columbia, MO
Bursicon is a heterodimeric neuropeptide responsible for mediating adult cuticle sclerotization and wing expansion via a G protein–coupled receptor (DLGR2) in diverse insect orders. Transcriptional studies revealed that both bursicon α and β transcripts were expressed in the central nerve system (CNS) of Drosophila larvae, pupae and newly emerged adults. Using DNA microarray and recombinant bursicon (r-bursicon), we have previously identified a set of bursicon-regulated genes in neck-ligated flies D. melanogaster. In the present study, we developed an in-vitro assay and explored the role of bursiocn in Drosophila larvae.

doi: 10.1603/ICE.2016.49159