Wednesday, December 12, 2007
D0587

Modulating properties of dust mite extracts on human dermal microvascular endothelial cells

Larry G. Arlian, larry.arlian@wright.edu, Aaron M. Newman, and Marjorie S. Morgan, marjorie.morgan@wright.edu. Wright State University, Department of Biological Sciences, 3640 Col. Glenn Hwy, Dayton, OH

This study demonstrated that components of house dust mite extracts influence the expression of adhesion molecules on endothelial cells and the secretion of IL-6, IL-8, and MCP-1 by normal human dermal endothelial cells and therefore may influence the course of an allergic reaction in the skin.


Species 1: Acari Pyroglyphidae Dermatophagoides farinae (American house dust mite)
Species 2: Acari Pyroglyphidae Dermatophagoides pteronyssinus (European house dust mite)