The Formosan subterranean termite, Coptotermes formosanus, is a serious pest where it has become established and is one of the most destructive insects in Louisiana. A pilot test was begun in 1998 in the French Quarter to demonstrate the effectiveness of using area wide management to reduce densities of termites. The pilot test is a cooperative effort between the LSU Agricultural Center, USDA-Agricultural Research Service and New Orleans Mosquito and Termite Control Board. All properties in a contiguous 15 block area in the French Quarter were treated using commercially available baits or non repellent termiticides. In 2002 the treatment zone was expanded to include the immediately surrounding blocks. Glue boards were used to estimate alate numbers and in-ground monitors for foraging activity. Alates were sampled once a week in April and two to three times weekly during the flight season (May through July 15) in 1998 through 2006. Monthly monitoring of foraging activity began in January, 1999 to determine the number of stations with termites. An overall 50% reduction in termite numbers and activity was observed. Isolated areas of “high” termite activity remain inside the test area. Inspections of properties using infrared and acoustic detection technologies and visual inspections of courtyards and trees are being conducted to detect and treat termites. A third and fourth expansion began in 2003 and 2006, respectively. Continued treatment, expansion, and monitoring are required to assess the long-term effects of the area wide management program.