The caddisfly subfamily Protoptilinae contains approximately 200 described species in 18 genera and has a rather disjunct distribution: 4 genera occur in the East Palearctic and Oriental regions, the remaining genera occur in the Nearctic and Neotropical regions. Prior to this study, monophyly for the subfamily and relationships among the genera were unclear. We constructed a phylogeny of Protoptilinae based on adult morphological data. Using maximum parsimony, a monophyletic Protoptilinae was recovered with the Neotropical genus Tolhuaca sister to all other protoptilines. Relationships among the Asian and Nearctic genera are unresolved, but the remaining Neotropical genera form a clade. The Caribbean genera also form a distinct clade. In addition to the morphological data, results from a preliminary molecular data set using mitochondrial CO1 sequences will be discussed.