The codling moth is one of the principal pests of apples in Michigan and elsewhere in the United States and the world. The primary means of control for codling moth is with insecticides. Despite the use of commercially labeled insecticides, Michigan apple growers have observed a steady increase in fruit injury over the last five years, suspected to be associated with insecticide resistance. Three populations of codling moth and seven insecticides were evaluated using diet surface bioassays with neonate larvae. To compare the resistant strains we used a susceptible strain collected from an orchard abandoned for 20 years. In addition, apple plots at the MSU Trevor Nichols Research Complex were treated with field rate doses of azinphosmethyl, lambda-cyhalothrin, methoxyfenozide, and acetamiprid to compare the residual activity of compounds when exposed to different codling moth populations. Treated fruit were collected 1h, 7d, 14d, 21d and 28d after field treatment and exposed to neonate larvae of two populations from commercial orchards: one with the highest levels of resistance and the second with lowest levels of resistance. Two populations of codling moth expressed 2 to 5-fold resistance to azinphosmethyl, 7 to 8-fold to phosmet, 6 to 10-fold to lambda- cyhalothrin, 14 to 16-fold to methoxyfenozide, 6-fold to indoxacarb, 2-fold to spinosad but not resistance to acetamiprid. Resistance to azinphosmethyl, lambda-cyhalothrin and methozyfenozide were also correlated with reduced residual activity in the field-treated bioassays. No differences in efficacy were found for acetamiprid. This broad-spectrum resistance is still at a relatively low level but presents serious problems for management of the codling moth.