Soybean cyst nematode (SCN), Heterodera glycines, and soybean aphid, Aphis glycines) can account for 30-50% soybean yield reductions in the north central United States. These pests have common geographical distribution and their life histories overlap during the growing season. Currently, nematodes and aphids are managed individually with no understanding of, or consideration for, the potential interactions that may occur between these two classes of soybean pests. Our goal is to elucidate if current IPM strategies need to be altered to account for the interaction of SCN and soybean aphid. Our objectives are to answer (1) if soybean aphids are more or less attracted to soybean infected with SCN than to noninfected plants, (2) if soybean aphid and SCN reproduction is greater in the presence of each other and if this interaction varies by the type of host genetics conferring SCN resistance, and (3) how these pests affect soybean yield quantity and quality. We report a series of experiments to address these objectives. Using laboratory-based, behavioral assays we have characterize soybean aphid orientation to soybeans infected and noninfected with SCN. Field experiments conducted in microplots established in noninfested or SCN-infested soil will address objectives 2 and 3. To address objective 3, entire microplots were caged and infected with either soybean aphids, SCN, both, or neither pest. Completion of these objectives will result in an expanded knowledge base that will lead to improved recommendations for managing both SCN and these insect pests of soybean.