Endo-symbiotic bacteria (endophytes), Harbaspirillum sp. B65 and Azospirillum sp. B510a induce infected rice plants to have systemic resistance against insect pests. As novel pest management tools to replace chemical insecticides, the use of endophytes in rice cultivation is now on trial to test its feasibility. Use of the endophytes enables us to reduce the cost and environmental risks of the insect pest management, while direct effects of the endophyte-infected rice plants on insect pests is less than traditional chemical pesticides. However, the use of the endophytes has some advantages such as safety for non-target organisms including natural enemies and long-lasting effectiveness. Therefore, its effectiveness must be discussed by taking indirect and durable effects into consideration. The rice brown planthopper (BPH) is one of the most injurious insect pests of rice plants in Japan. To discuss the usefulness of the endophyte application in managing BPH, its inclusive effect was investigated using simulation models of BPH population dynamics. The simulation results suggest that sole use of the endophyte-infected rice plants may not always regulate BPH density below the economic injury level successfully. It follows that additional control measures are needed in cases where immigrant BPH density is high.