Tuesday, December 12, 2006
D0316

Identification of a pan-allergen of storage and house dust mites

DiAnn L. Vyszenski-Moher, diann.vyszenski-moher@wright.edu, Larry G. Arlian, larry.arlian@wright.edu, Marjorie S. Morgan, marjorie.morgan@wright.edu, and Denada Sharra, sharra.2@wright.edu. Wright State University, Department of Biological Sciences, 3640 Col. Glenn Hwy, Dayton, OH

We investigated the issue of species-specific and cross-reactive allergens between several common species of storage and house dust mites to which humans are exposed. We determined that some of the cross-allergenicity is due to a pan allergen that makes these mites cross-reactive with one another and with other invertebrates such as shrimp.


Species 1: Acari Acaridae Acarus siro (grain mite, storage mite)
Species 2: Acari Acaridae Tyrophagus putrescentiae (mold mite, storage mite)
Species 3: Acari Pyroglyphidae Dermatophagoides farinae (American house dust mite)