Monday, 15 November 2004 - 9:18 AM
0044

Potential role of mosquito Aedes aegypti sterol carrier protein-2 in vitellogenesis

Irina Vyazunova, vyazunov@entomology.wisc.edu, E.J. Blitzer, and Que Lan, qlan@entomology.wisc.edu. University of Wisconsin Madison, Entomology, 1630 Linden Drive, 840 Russell labs, Madison, WI

A blood meal is necessary for egg production in Ae. aegypti. Transcription of AeSCP-2 (sterol carrier protein –2) was investigated in sugar fed and blood-fed mosquitoes. The levels of AeSCP-2 mRNA increased dramatically in the gut, the ovary and fat body by 5 hours after a blood meal. These results indicate that AeSCP-2 might be involved in vitallogenesis. The knockdown of AeSCP-2 expression using AeSCP-2 RNAi was performed in Ae. aegypti. The effect of AeSCP-2 silencing suggests that AeSCP-2 is important for Ae.aegypti adult development and reproduction.


Species 1: Diptera Culicidae Aedes aegypti (yellow fever mosquito)
Keywords: vitellogenesis

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