Pest Management Professionals (PMP’s) have recently had the opportunity to use newer, non-repellent active ingredients for subterranean termite control. These active ingredients provide control through reduction of termite populations in and associated with the target structures. The pest control industry has asked if the newer non-repellents may provide acceptable control of subterranean termites with less than full-conventional treatments. One approach being evaluated is treatment application consisting of exterior perimeter with localized interior treatments of dilution. In this study, 43 termite infested structures were treated with Termidor WG or SC Termiticide/Insecticide (fipronil: phenyl pyrazole) using either an Exterior Perimeter Treatment (EP) or Exterior Perimeter with Localized Interior Treatment (EP/LIT). Forty-one of the structures exhibited no activity from 1st inspection date post treatment through January 2004 (18-36 MAT). One EP site had recurring activity at 12 MAT at an interior penetration not treated at time of initial treatment. Another EP site had continuing activity at an interior site not treated at initial treatment through 6 MAT. All of the structures that received the EP/LIT, which included treatments at the points of termite activity, exhibited 100% control through the course of this study. According to this study, depending on foundation type, PMP’s can expect to use 19%-48% less diluted material when using an EP/LIT approach versus a full conventional treatment.