Wednesday, 29 October 2003
D0596

This presentation is part of : Display Presentations, Section D. Medical and Veterinary Entomology

Repeated infestation of mice with Amblyomma americanum nymphs does not induce anti-tick resistance

Amanda D. Loftis, Danielle E. Ross, and Michael L. Levin. Centers for Disease Control and Prevention, Atlanta, GA, Viral and Rickettsial Zoonoses Branch, 1600 Clifton Rd., MS-G13, Atlanta, GA

An experiment was performed to determine if laboratory mice can be infested multiple times with A. americanum ticks, as is commonly done in pathogen transmission studies using Ixodes scapularis ticks. Laboratory mice (Mus musculus, BALB/c strain) were infested five times with A. americanum nymphs. The first four infestations were staged at 7 day intervals; the final infestation was performed after a 14-day tick-free period. The effect of multiple infestations on tick viability was monitored by: tick feeding success, days to engorgement, engorged tick weight, molting success, and time to molt. After the fifth infestation, there was no change in tick viability compared to the first infestation, indicating that mice do not develop resistance to A. americanum nymphs.

Species 1: Acari Ixodidae Amblyomma americanum (lone star tick)
Keywords: Anti-tick Immunity, Mouse

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