Isolation and characterization of Manduca sexta sterol carrier protein-x (SCP-x) gene
Min-Sik Kim, firstname.lastname@example.org and Que Lan, email@example.com. University of Wisconsin - Madison, Entomology, 840 Russell Labs. 1630 Linden Drive, Madison, WI
Cholesterol is very important for cellular membranes and ecdysteroids biosynthesis in insects. The sterol carrier protein SCP-x/SCP-2 has been speculated to have functions in intracellular movement of cholesterol and other lipids species. We have isolated the Manduca sexta sterol carrier protein x (MsSCP-x) cDNA. The MsSCP-x has a 3-ketoacyl CoA thiolase and SCP-2 domains. MsSCPx shares 80%, 79% and 64% similarity to Bombyx mori SCPx, Spodoptera littoralis SCPx and Aedes aegypti SCPx, respectively in the conserved domain.
Species 1: Lepidoptera Sphingidae Manducasexta (tobacco hornworm)