Plum curculio, Conotrachelus nenuphar, is a major pest of stone and pome fruits. Stone fruits are also plagued by clear-winged moths (Lepidoptera: Sesiidae), e.g., peachtree borer (Synanthedon exitiosa) and lesser peachtree borer (Synanthedon pictipes). Entomopathogenic nematodes have potential as alternative management tactics for these pests. Soil applications of entomopathogenic nematodes can control plum curculio larvae, e.g., applications of Steinernema riobrave have produced 78-100% control in peach orchards and wild plum thickets. Entomopathogenic nematodes are virulent to both lesser peachtree borer and peachtree borer. Field applications with S. carpocapsae have resulted in 88-100% peachtree borer control. Field tests have been initiated to determine efficacy in controlling lesser peachtree borer with nematode applications. Additional research is required to incorporate these microbial control tactics into IPM programs.