Balochistan melon fruit fly (Myiopardalis pardalinat) is one of the major pests of muskmelon (Curcumas melo) cultivated under rain fed conditions in Pakistan. Field study was carried out to evaluate efficacy of bait (protein hydrolysate) vs. synthetic insecticide (endosulfan 35EC) when applied judiciously along the periphery of host and non-host fauna, before and after fruit setting stage. The results revealed significant reduction in fruit infestation when compared with untreated check. Percent fruit infestation/ fruit yield in plots treated with synthetic insecticide and bait spray were 1.65%/212Kg and 2.54%/199Kg. respectively as compared to check (25.63 %/ 31.45 kg).