Recent advances in molecular biology have made gene silencing in insects a reality. RNA interference (RNAi) is the primary tool available for this purpose. In termites, RNAi is a proven research tool that has begun to elucidate molecular mechanisms of termite sociality. However, while it is a proven research tool, the utility of RNAi as a tool for termite control remains to be fully realized. Perceived barriers include target identification, delivery strategies, safety to non-target organisms, and acceptance by the public and regulatory agencies. This presentation will overview recent successes, as well as provide a synopsis of currently perceived barriers.