The glassy-winged sharpshooter, GWSS, has been shown to be susceptible to insect virus infections. A new virus was isolated from field caught GWSS and partially sequenced. Sequence identity showed that this was a new sharpshooter virus separate from those already reported by Hunter et. al. 2004, and has been named Homalodisca Coagulata Virus-2, HoCV-2. Sharpshooter viruses reduce leafhopper survival by increasing nymphal mortality, especially during the molt to adult, and are contributing to the slow reduction in sharpshooter populations throughout southern California. The virus genome is being completed and the various viral proteins evaluated for insect toxicity. New discoveries such as these are aiding efforts to manage the GWSS and other leafhopper vectors of Pierce’s Disease, and aim to reduce the spread of other Xylella caused diseases.