Varroa mites, an obligate parasite of the honey bee, has been responsible for the decline in managed and feral colonies throughout the United States. As the eradication of varroa from honey bee colonies is unlikely, the goal is to limit the population growth of varroa. Because honey bee and mite reproduction is linked, preventing the laying of eggs by the queen will prevent egg laying by founderess mites. To test the impact disrupting honey bee and mite reproduction on honey bee and mite population size we randomly assigned colonies to six different treatments: 1) controls, 2) requeen, queen released in three days, 3) requeen, queen released in 15 days, 4) requeen, queen released in 21 days, 5) dequeen, emergency queen replacement, and 6) cage existing queen and release in 15 days. In 2004 treatments were implement during the first week of July in all locations and in 2005 treatments were implement during the first week of July in Delaware and Maryland and during the third week of July in central Pennsylvania. In 2005, drone comb was inserted into colonies when the queens were released and removed after the brood was capped. While summer queen replacement/confinement and drone removal has potential for varroa control, dequeening/requeening is time consuming and replacing the existing queen each year is unnecessary. A possible advantage to summer queen replacement/confinement is requeening would occur later than is typical thus reducing the cost of queens.