Aphid-transmitted plant viruses cause major losses in cucurbit crops in Florida, particularly in the fall growing season. Two new varieties of calabaza, Cucurbita moschata, were found to remain free of virus symptoms in fall pumpkin trials in Florida in 2002 when all other varieties were infected. When plants of the varieties El Dorado and La Estrella were mechanically inoculated in the greenhouse with sap from plants infected with watermelon mosaic virus (WMV), zucchini yellow mosaic virus (ZYMV), or the watermelon strain of papaya ringspot virus (PRSV-W), they developed few symptoms. While neither variety was immune (as shown by ELISA), virus titers were greatly reduced, particularly in El Dorado. Experiments with aphid transmission of these viruses are being conducted to determine if resistance to aphids is also involved.