Single nucleotide polymorphism (SNP) genotyping has been carried out by various methods, including differential hybridization such as allele-specific oligonucleotide hybridization and fluorescent probes (molecular beacon, TaqMan); melting temperature-based analyses such as single-stranded conformational polymorphism (SSCP), heteroduplex analysis, DHPLC and fluorescence melting curves; allele-specific amplification; and DNA sequencing or primer extension to distinguish alleles. All these methods are either cumbersome to perform or expensive in both the equipment and reagents required. We have developed a method based on fluorescence-labeled allele specific probes. The alleles can be simply visually distinguished on agarose gel after amplification of genomic DNA.