The striped, Acalymma vittatum (F.), and spotted, Diabrotica undecimpunctata howardi Barber, cucumber beetles (Coleoptera: Chrysomelidae) are vector of a bacterium, Erwinia tracheiphila (E.F. Smith) Holland, which cause bacterial wilt on cucurbits. Managing cucumber beetles on muskmelons is intensive because muskmelons are highly susceptible to bacterial wilt. The only way to avoid the disease is to prevent the beetles from feeding on the plants. Field studies were conducted in southern Indiana to develop alternative technique for sampling, to investigate optimal time for direct scouting, and to determine the efficacy of insecticides in managing cucumber beetles on muskmelons from 2001 through 2004. The results of the sampling studies indicated that yellow sticky trap can be used to sample the beetles on muskmelons; on an average of 20 beetles collected on trap within 48-hour is equivalent to one beetle per plant in the field. Furthermore, the optimal time for direct scouting beetles on plants is from 12 to 2 PM. The results of insecticide trials demonstrated that treatments applied with soil insecticides during or before transplanting the melons and spray foliar insecticides only when the beetle number is approached to or above the economic threshold of one beetle per plant had less bacterial wilt incidence and higher yield. A recommended integrated pest management program for the cucumber beetles and bacterial wilt on muskmelons is discussed.