The lesser peach tree borer (Synanthedon pictipes) historically has been a secondary, indirect pest of peach in the southeastern US. Recently this pest has become a serious primary pest in central Georgia peach orchards and threatens production through significant reduction of tree vigor and orchard longevity. Management of the lesser peach tree borer was examined in 2004 and 2005 using mating disruption. Early and midseason applications of Isomate-L pheromone dispensers decreased capture of male moths in pheromone-baited traps. In addition, numbers of pupal exuviae per limb were reduced. However, dissection of females revealed that mating occurred in treated orchards.