Adoption of Bt corn in the Mid-southern region has increased rapidly in recent years because of emerging corn stalk borer problems in the region, especially the increasing problems of sugarcane borer (SCB) in Louisiana. The currently adopted “high dose/refuge” resistance management strategy for Bt corn was developed for management of Bt resistance in European corn borer (ECB) and Southwestern corn borer (SWCB). Field and laboratory data have demonstrated that SCB is much less susceptible to Bt toxins in Bt corn plants than ECB and SWCB. It is, therefore, important to verify if the currently used “high dose/refuge” strategy is a valid approach for management of Bt resistance in SCB. A highly Bt resistant SCB strain has been selected in the laboratory in Louisiana. In this study, larval survival of the homozygous Bt-resistant, heterozygous Bt-resistant and Bt-susceptible SCB on corn leaf tissues and on whorl- and reproductive-stage plants of seven Bt-corn and five non-Bt corn hybrids were evaluated in the laboratory and greenhouse to determine if these Bt-corn cultivars qualify as “high dose” Bt corn against SCB.