The aphids Myzus persicae (Sulzer) and Macrosiphum euphorbiae (Thomas) are two major pests of potato culture. Although direct phloem sap feeding may cause yield losses, virus transmission is responsible for most problems encountered, especially for seed-producing fields. Searching for natural sources of resistance in wild Solanum species is one of the most promising way to develop alternative and sustainable methods to control aphids. In the laboratory we quantified resistance of fourteen accessions (i.e. five wild potato species) obtained from the USDA-Potato Germplasm Introduction Station of Sturgeon Bay, Wisconsin., against M. persicae and M. euphorbiae. The procedure was done under controlled conditions that allowed to reduce variability of environmental parameters and results. The five wild Solanum species tested (Solanum chomatophilum, S. stoloniferum, S. bukasovii, S. marinasense and S. medians) induced more than 90% of M. persicae nymphal mortality. Only three wild species (S. chomatophilum, S. stoloniferum and S. medians) led to such M. euphorbiae mortality rate. When enough adult aphids emerged (only for M. euphorbiae on S. bukasovii and S. marinasense) the intrinsic rate of natural increase (rm) was significantly reduced for most wild Solanum accessions used as food supply. All accessions tested showed interesting resistance levels that could be potentially amenable to aphid potato management.