We evaluated several deployment strategies for using transgenic corn for control of western corn rootworm from both a biological and economic perspective. In areas with rotation-resistant phenotypes, the standard management strategy is to plant transgenic corn in rotated cornfields; in areas without rotation-resistant phenotypes, the standard strategy is to plant transgenic corn in continuous cornfields. We compared the standard strategies with a strategy where the proportion of transgenic corn in the region increases over time as well as a strategy of determining single or 15-year economic thresholds for using transgenic crops. Using economic thresholds, if populations are below the threshold then transgenic corn is not planted in the region the following year. In some cases, especially when the allele for resistance to crop rotation, Y, is recessive, the dynamic management strategies generated greater returns than the standard strategy. This occurred when returns from not planting transgenic corn each year exceeded losses due to increased larval damage. Determining 15-year economic thresholds that took into account genetics and density-dependent survival was generally a better management strategy than the standard strategies or using single-year economic thresholds.