Giant foxtail, Setaria faberi, is an economically important weed throughout much of the U.S. Corn Belt. Diversified cropping systems may reduce foxtail seed banks by encouraging seed predation from insects. In this research we examined the effects of cropping systems on invertebrate seed predation in a conventional, two-year corn/soybean rotation and a reduced-input, four-year corn/soybean/triticale/alfalfa rotation system. Preliminary data suggest that ground crickets (Orthoptera: Gryllidae) and ground beetles (Coleoptera: Carabidae) may be the major invertebrate seed predators in central Iowa, though these taxa appear to be less important as seed predators than vertebrates, especially rodents. Laboratory studies conducted during 2004 examined whether traditional methods of measuring invertebrate seed predation may affect invertebrate behavior and underestimate predation rates