Instead of proceeding with the traditional isolation and identification from hosts of individual mosquito attractants, ISCA Technologies, Inc. created compositions which mimic the skin of the specific vertebrate hosts. Most mosquitoes apparently exhibit some level of host ‘preference’, i.e., they do not feed indiscriminately on any vertebrate hosts. An innate ‘preference’ for odor blends of a certain host species has been examined on only few occasions. In these studies, host-feeding patterns within a closely related species complex were found to be odor mediated and were attributed to a differential response to CO2 and other skin odors, which has both a sensory, physiological and innate olfactory basis. The actual bait, created through a process patented by ISCA, provides the host seeking Aedes aegypti a much more complete “olfactory sensation” associated to its specific “host” (humans) than other attractants which rely soley CO2 and/or octenol. Traps lured with this bait containing a more “sensory complete” profile of humans triggers rapid responses from Ae. aegypti inducing the full set of host seeking (activation) and feeding (actual probing and imbibing of lure) behaviors. When baited with only the ISCA lure, omitting even the synergistic effect of CO2, our trap has proven to be superior to the Fay-Prince and Wilton traps and three other commercial traps in competitive laboratory trap tests. Laboratory studies indicate the capture rate of this prototype baited with this new lure closely approximates the rates obtained from human landing / biting counts for the same mosquito density.