Reproduction in insects requires precise endocrine coordination. In most dipteran species, including mosquitoes, both juvenile hormone (JH) and ecdysteroids play roles in mediating nutrition and oogenesis. In anautogenous mosquitoes two nutritional time points seem to mediate hormonal regulation: 1) larval reserves may be activating corpora allata (CA) cells to secrete JH to induce competency in ovaries and fat body, and 2) a blood meal is thought to activate release of peptide factors from the brain to stimulate ovarian secretion of ecdysteroids. In autogenous mosquitoes, larval reserves must interplay with the endocrine system to regulate oogenesis but this has not been well studied. We examined how larval and adult nourishment mediates the endocrinological events associated with egg development in autogenous Ochlerotatus atropalpus and anautogenous Aedes aegypti.