Concern for the impact of widespread broadcast use of pesticides on health and the environment, together with an increasing awareness of the risks by an increasing chemophobic public has provided impetus for the research, development and commercialization of alternative pest control strategies. Such alternative strategies look to mitigating the risk of the widespread use of conventional insecticides by the use of microbial agents, plant incorporated protectants, the use of pheromones and other semiochemicals including plant extractives and essential oils. "Attract and Kill" is one strategy making use of semiochemicals in conjunction with small amounts of conventional insecticide in such manners as to preclude atmospheric and environmental exposure with concomitant risk reduction. Since the commercialization of these strategies is being pursued by, in the main, small, undercapitalized, entrepreneurial companies a major hurdle to market introduction is the cost and time required to complete the regulatory process. Strategies for the registration of the various types of "attract and kill" products in the United States will be discussed in light of the various concessions granted to semiochemicals and other biological chemicals since 1982 through to the Pesticide Registration Improvement Act of 2004, the provisions of which became effective on March 23, 2004. In addition to the effect of the "fee for service" provisions of PRIA, other items which will be discussed are FIFRA 25(b) [minimum risk pesticides] active ingredients and inert materials; the use of semiochemicals in traps, tolerance status for pheromones and semiochemicals, and registration requirements and how they should be addressed.