The incidence of many human mosquito-borne diseases such as dengue and malaria is increasing annually, yet the number of effective insecticides available for mosquito control is dwindling. Furthermore, little is known about how well insecticides that are marketed for use against agricultural pests perform against mosquitoes. To address this issue, several novel insecticides, including spinosad, imidacloprid, diafenthiuron, indoxacarb, chlorfenapyr, hydramethylnon, pyriproxyfen and tebufenozide, were tested against Aedes aegypti larvae (based on 72 hour mortality and prevention of adult emergence) and adults (based on 48 hour mortality). The most effective larvicides (based on 72 hour mortality) were spinosad, imidacloprid and chlorfenapyr. The only effective adulticides were spinosad and imidacloprid. The effect of the P450 inhibitor, piperonyl butoxide, on toxicity of these insecticides also will be presented.
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