In laboratory tests, four experimental formulations each of IR3535 (ethyl butylacetylaminopropionate) and DEET (diethyltoluamide) were compared for their repellency against adult Aedes aegypti and Culex quinquefasciatus mosquitoes. Each active ingredient was formulated as a 10% and 20% creme and an alcohol spray for a total of 8 products tested. Eight volunteers participated in the study. The forearm of each individual was treated with a formulation while the other forearm was not treated and served as a control. Once treated a 10-minute "aging" period was observed before testing commenced. At about 15 min intervals each arm was separately exposed to fifty non-blood fed mosquitoes (of each species) in separate 25.5 (w) x 33 (l) x 25.7 (h) cm2 screened metal cages. Time to the first and second consecutive bite was the criteria for determining repellent efficacy. It appeared that time to bite for both concentrations and formulations of IR3535 were comparable to DEET for both mosquito species. Data will be presented on duration of repellency. Interestingly, longer protection times from bites with both products were evident for Cx. quinquefasciatus compared with Ae. aegypti.
Species 1: Diptera Culicidae Aedes aegypti (yellow fever mosquito)
Species 2: Diptera Culicidae Culex quinquefasciatus (southern house mosquito)
Keywords: mosquito, repellents
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