Permethrin resistance was investigated in head louse populations from California, Florida and Texas. Resistance frequency based on insecticide impregnated filter-paper bioassay is 41, 87 and 89%, respectively. Genotyping analysis showed that T929I and L932F mutations are tightly linked together and the resistant allele frequency by analysis of these mutations is 55, 96 and 91, respectively. The resistance gene is recessive. Presence of resistant homozygotes correlated quite well with the permethrin resistant phenotype, indicating altered voltage-gated sodium channel gene plays a major role in permethrin resistance in human head lice.
Species 1: Phthiraptera Pediculidae Pediculus capitis (human head louse)
Keywords: insecticide resistance
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