Monday, 18 November 2002
D0211

This presentation is part of : Display Presentations, Section D. Medical and Veterinary Entomology

Presence of serum IgE to storage mites among dogs with atopic dermatitis

Larry G. Arlian1, R. Jeffrey Schumann1, Marjorie Morgan1, and Robert Glass2. (1) Wright State University, Department of Biological Sciences, 3604 Col. Glenn Highway, Dayton, OH, (2) Biomedical Services, 3921 Steck Ave. #A101, Austin, TX

This study showed that most dogs with atopic dermatitis have serum IgE to several species of storage mites. Immunoblotting using sera from 84 atopic dogs was used to identify proteins in mite extracts that bound IgE. Ninety-four percent of the dogs had IgE that recognized proteins in extracts of 1 or more of the storage mite species. Ninety-five, 92, and 89% of the storage mite sensitive dogs had serum IgE that recognized proteins in extracts of A. siro, B. tropicalis, and T. putrescentiae respectively. Eighty-two percent had serum IgE that recognized at least one protein in all 3 species. Most of the major allergens had molecular weights > 80 kd.

Species 1: Acari Acaridae Acarus siro
Species 2: Acari Acaridae Tyrophagus putrescentiae
Species 3: Acari Echimyopididae Blomia tropicalis
Keywords: storage mite, stored products

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