Monday, 18 November 2002 - 1:00 PM
0520

This presentation is part of : Student Competition Ten-Minute Papers, Section D. Medical and Veterinary Entomology

Population structure of an emerging Neotropical malaria vector, Anopheles marajoara

Meg Lehr1, Jan E. Conn2, Richard C. Wilkerson3, and C. William Kilpatrick1. (1) University of Vermont, Biology Department, 120A Marsh Life Sciences, Burlington, VT, (2) Wadsworth Center, Griffin Laboratory, New York State Department of Health, 5668 Farm Road, Slingerlands, NY, (3) Smithsonian Institution, Walter Reed Biosystematics Unit, Museum Support Center, MRC 534, Washington, DC

With increased infection rates coupled with reversed relative abundances since the 1940s, Anopheles marajoara has replaced An. darlingi as the major malaria vector around the city of Macapá (Amapá state, Brazil). In order to determine the population genetic structure and population history of this vector, adult biting females were collected from 5 sites in the Brazilian states of Pará and Amapá and a 766 base pair fragment of the mitochondrial cytochrome oxidase I (COI) gene was amplified and sequenced for 10 to 15 specimens per collection site. Ten of 766 sites were variable, of which nine were transition mutations and one was a transversion mutation. Eleven COI haplotypes were identified among 59 individuals sequenced. The most frequent haplotype (n=45) was found at all collection sites, and 8 haplotypes were observed at low frequency (n=1 each) and were unshared among sites. The geographic distribution of haplotypes and a starlike minimum spanning network indicate that An. marajoara has undergone a relatively recent demographic sweep caused by a range expansion from the north.

Species 1: Diptera Culicidae Anopheles marajoara
Keywords: Cytochrome Oxidase

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