Wednesday, December 12, 2001 -
D0574

A survey of Australian Boophilus microplus for the presence of mutations in sodium channel and esterase genes found in Mexican strains

Andrew C Chen1, Haiqi He1, and Shirley Jones2. (1) USDA ARS, Veterinary Entomology Research Laboratory, 2881 F&B Rd, College Station, TX, (2) Queensland Department of Primary Industries, 280 Grindle Rd, Wacol, Queensland, Australia

Certain Mexican strains of Boophilus microplus (Corrales, C; San Felipe, S) with extremely high resistance to pyrethroid acaricides have a single point mutation in their sodium channel gene. Another Mexican strain (Coatzacoalcos, Cz) has a moderate level of resistance to pyrethroids and a point mutation in an esterase gene has been found in this strain. The mutation in the tick sodium channel gene does not involve a restriction endonuclease cleavage site and is therefore not possible to detect with conventional restriction fragment length polymorphism (RFLP) analysis. In contrast, the mutation in the esterase gene creates a restriction site (EcoRI) not found in the wild type gene. We have developed polymerase chain reaction (PCR)-based methods to detect the presence of these mutations in tick larvae. These methods are highly sensitive, capable of detecting the mutation in unfed individual larvae. None of individuals from various Australian strains contain these mutations when screened with these methods.

Species 1: Acarina Ixodidae Boophilus microplus (southern cattle tick)
Keywords: PCR, RFLP

The ESA 2001 Annual Meeting - 2001: An Entomological Odyssey of ESA