Wednesday, December 12, 2001 -
D0711

Differential repellent effects of DEET, AI3-37220 racemate and its stereoisomers against mosquitoes and a sand fly

Jerome A. Klun1, Daniel Strickman2, Edgar Rowton2, Jack Williams2, and Mustapha Debboun2. (1) USDA-ARS, Chemicals Affecting Insect Behavior Laboratory, Beltsville Ag. Res. Center, 10300 Baltimore Ave, Beltsville, MD, (2) Walter Reed Army Institute of Research, Department of Entomology, Building 503, Robert Grant Avenue, Walter Reed Army Medical Center, Washington, DC

Laboratory bioassays using the K & D module and human volunteers showed that repellent effects vary significantly from one fly species to another. Tests showed that Aedes aegypti was repelled from biting at skin-applied doses that were one tenth the doses of DEET or racemic AI3-37220 needed to repel Anopheles albimanus. Tests of the four stereoisomers of AI3-37220 showed that the 1S, 2'S stereoisomer was more effective than the other three stereoisomers in deterring the biting responses of Aedes aegypti, Anopheles stephensi, Aedes albopictus, and Phlebotomus papatasi.

Species 1: Diptera Culicidae Aedes aegypti (yellow fever mosquito)
Species 2: Diptera Culicidae Anopheles stephensi
Species 3: Diptera Culicidae Aedes albopictus (Asian tiger mosquito)
Keywords: N,N-diethyl-m-toluamide

The ESA 2001 Annual Meeting - 2001: An Entomological Odyssey of ESA