The anthranilamide class of insecticides represents a novel chemistry that act with outstanding selectivity on the ryanodine receptor in insects. CORAGENTM SC is a member of the anthranilamide chemistry discovered and being commercialized by Dupont Crop Protection. CORAGEN^TM SC is highly potent and has shown broad-spectrum control of Lepidopteran crop pest species. In addition to its outstanding activity on Lepidoptera, CORAGEN^TM SC has shown varied levels of efficacy on selected crop pest species in the order Coleoptera, Diptera, and Homoptera. Within Homoptera, CORAGEN^TM SC has been most consistent in providing efficacy and crop protection against key whitefly species, i.e., Bemisia tabaci and B. argentifolii. Under laboratory and field conditions, the level of efficacy on whiteflies with CORAGEN^TM SC varies with the method of application (i.e., foliar spray versus root uptake), the ability of the foliar spray to penetrate the leaf cuticle (translaminar movement), the intensity of the infestation, and the timing of the application in relation to pest pressure. CORAGEN^TM SC acts primarily via ingestion on whitefly nymphs. Although adult whiteflies are not directly controlled, feeding behavior and reproduction are affected. Field efficacy tests conducted around the world indicate that in addition to its outstanding efficacy on Lepidopteran pests, CORAGEN^TM SC can be a valuable tool for the management of key whitefly species, providing inhibition of virus transmission and overall crop protection. Laboratory and field efficacy results on fruiting vegetables and cucurbit crops will be presented.